DOAJ Open Access 2021

Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

Mengfei Liu Sheng Cao Li He Jinhang Gao Juan P. Arab +17 lainnya

Abstrak

Alcoholic hepatitis is characterized by intense liver inflammation driven by excessive cytokines and chemokines production and immune cell infiltration. Here the authors identify a super-enhancer that regulates the expression of multiple CXCL chemokines in alcoholic hepatitis and may be a potential therapeutic target.

Topik & Kata Kunci

Science

Penulis (22)

Mengfei Liu

Sheng Cao

Li He

Jinhang Gao

Juan P. Arab

Huarui Cui

Weixia Xuan

Yandong Gao

Tejasav S. Sehrawat

Feda H. Hamdan

Meritxell Ventura-Cots

Josepmaria Argemi

William C. K. Pomerantz

Steven A. Johnsen

Jeong-Heon Lee

Fei Gao

Tamas Ordog

Philippe Mathurin

Alexander Revzin

Ramon Bataller

Huihuang Yan

Vijay H. Shah

Format Sitasi

APA MLA BibTeX

Liu, M., Cao, S., He, L., Gao, J., Arab, J.P., Cui, H. et al. (2021). Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis. https://doi.org/10.1038/s41467-021-24843-w

Akses Cepat

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Informasi Jurnal

Tahun Terbit: 2021
Sumber Database: DOAJ
DOI: 10.1038/s41467-021-24843-w
Akses: Open Access ✓