DOAJ Open Access 2021

Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

A. S. Deshmukh D. E. Steenberg M. Hostrup J. B. Birk J. K. Larsen +9 lainnya

Abstrak

Skeletal muscle conveys the beneficial effects of physical exercise but due to its heterogeneity, studying the effects of exercise on muscle fibres is challenging. Here, the authors carry out proteomic analysis of myofibres from freeze-dried muscle biopsies, show fibre-type specific changes in response to exercise, and show that the oxidative and glycolytic muscle fibers adapt differentially to exercise training.

Topik & Kata Kunci

Penulis (14)

A

A. S. Deshmukh

D

D. E. Steenberg

M

M. Hostrup

J

J. B. Birk

J

J. K. Larsen

A

A. Santos

R

R. Kjøbsted

J

J. R. Hingst

C

C. C. Schéele

M

M. Murgia

B

B. Kiens

E

E. A. Richter

M

M. Mann

J

J. F. P. Wojtaszewski

Format Sitasi

Deshmukh, A.S., Steenberg, D.E., Hostrup, M., Birk, J.B., Larsen, J.K., Santos, A. et al. (2021). Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training. https://doi.org/10.1038/s41467-020-20556-8

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Informasi Jurnal
Tahun Terbit
2021
Sumber Database
DOAJ
DOI
10.1038/s41467-020-20556-8
Akses
Open Access ✓