DOAJ Open Access 2020

High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli

Tomoya Maeda Junichiro Iwasawa Hazuki Kotani Natsue Sakata Masako Kawada +4 lainnya

Abstrak

Understanding evolutionary constraints in antibiotic resistance is crucial for prediction and control. Here, the authors use high-throughput laboratory evolution of Escherichia coli alongside machine learning to identify trade-off relationships associated with drug resistance.

Topik & Kata Kunci

Penulis (9)

T

Tomoya Maeda

J

Junichiro Iwasawa

H

Hazuki Kotani

N

Natsue Sakata

M

Masako Kawada

T

Takaaki Horinouchi

A

Aki Sakai

K

Kumi Tanabe

C

Chikara Furusawa

Format Sitasi

Maeda, T., Iwasawa, J., Kotani, H., Sakata, N., Kawada, M., Horinouchi, T. et al. (2020). High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli. https://doi.org/10.1038/s41467-020-19713-w

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Informasi Jurnal
Tahun Terbit
2020
Sumber Database
DOAJ
DOI
10.1038/s41467-020-19713-w
Akses
Open Access ✓