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DOAJ Open Access 2018

NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence

Aled J. Parry Matthew Hoare Dóra Bihary Robert Hänsel-Hertsch Stephen Smith +9 lainnya
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Abstrak

Notch can drive senescence in a cell contact dependent manner. Here the authors show that NOTCH signalling can modulate chromatin structure autonomously and non-autonomously via the JAG1-NOTCH-HMGA1 interplay during senescence.

Topik & Kata Kunci

Science

Penulis (14)

A

Aled J. Parry

M

Matthew Hoare

D

Dóra Bihary

R

Robert Hänsel-Hertsch

S

Stephen Smith

K

Kosuke Tomimatsu

E

Elizabeth Mannion

A

Amy Smith

P

Paula D’Santos

I

I. Alasdair Russell

S

Shankar Balasubramanian

H

Hiroshi Kimura

S

Shamith A. Samarajiwa

M

Masashi Narita

Format Sitasi

APA MLA BibTeX
Parry, A.J., Hoare, M., Bihary, D., Hänsel-Hertsch, R., Smith, S., Tomimatsu, K. et al. (2018). NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence. https://doi.org/10.1038/s41467-018-04283-9

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Informasi Jurnal
Tahun Terbit
2018
Sumber Database
DOAJ
DOI
10.1038/s41467-018-04283-9
Akses
Open Access ✓