DOAJ Open Access 2017

Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics

Nicolas Bertrand Philippe Grenier Morteza Mahmoudi Eliana M. Lima Eric A. Appel +5 lainnya

Abstrak

Understanding the interaction between nanoparticles and biomolecules is crucial for improving current drug-delivery systems. Here, the authors shed light on the essential role of the surface and other physicochemical properties of a library of nanoparticles on their in vivo pharmacokinetics.

Topik & Kata Kunci

Penulis (10)

N

Nicolas Bertrand

P

Philippe Grenier

M

Morteza Mahmoudi

E

Eliana M. Lima

E

Eric A. Appel

F

Flavio Dormont

J

Jong-Min Lim

R

Rohit Karnik

R

Robert Langer

O

Omid C. Farokhzad

Format Sitasi

Bertrand, N., Grenier, P., Mahmoudi, M., Lima, E.M., Appel, E.A., Dormont, F. et al. (2017). Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics. https://doi.org/10.1038/s41467-017-00600-w

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Informasi Jurnal
Tahun Terbit
2017
Sumber Database
DOAJ
DOI
10.1038/s41467-017-00600-w
Akses
Open Access ✓