DOAJ Open Access 2021

Long-term ecotoxicological effects of ciprofloxacin in combination with caffeine on the microalga Raphidocelis subcapitata

Vinicius Diniz Gabriela Rath Susanne Rath Caio Rodrigues-Silva José R. Guimarães +1 lainnya

Abstrak

Ciprofloxacin (CIP) is an antimicrobial “pseudo-persistent” in aquatic ecosystems. Once dispersed in the water compartments, it can also affect the microalgae. Thus, the evaluation of its long-term ecotoxicological effects is necessary. CIP interactions with other pharmaceuticals are not well known. In this study, we investigated the toxic effects of CIP alone and combined with caffeine (CAF), using the modified Gompertz model parameters and the chlorophyll-a production of the microalga Raphidocelis subcapitata as endpoints, throughout a 16-day exposure assay. The exposure to CIP alone led to significant reductions of the growth rate and the cell density of the microalgae compared to control groups. The combination with CAF lowered the adverse effects of CIP to R. subcapitata. However, as the toxicity is dynamic, our results indicated that the toxic effects in respect to the studied endpoints changed throughout the exposure period, reinforcing the need for longer-term ecotoxicity assessments.

Topik & Kata Kunci

Toxicology. Poisons

Penulis (6)

Vinicius Diniz

Gabriela Rath

Susanne Rath

Caio Rodrigues-Silva

José R. Guimarães

Davi G.F. Cunha

Format Sitasi

APA MLA BibTeX

Diniz, V., Rath, G., Rath, S., Rodrigues-Silva, C., Guimarães, J.R., Cunha, D.G. (2021). Long-term ecotoxicological effects of ciprofloxacin in combination with caffeine on the microalga Raphidocelis subcapitata. https://doi.org/10.1016/j.toxrep.2021.02.020

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Informasi Jurnal

Tahun Terbit: 2021
Sumber Database: DOAJ
DOI: 10.1016/j.toxrep.2021.02.020
Akses: Open Access ✓