DOAJ Open Access 2015

Genome-wide analysis of potential cross-reactive endogenous allergens in rice (Oryza sativa L.)

Fang Chao Zhu Rui Zong Jia Lin Xu Hua Kong Yun Ling Guo +3 lainnya

Abstrak

The proteins in the food are the source of common allergic components to certain patients. Current lists of plant endogenous allergens were based on the medical/clinical reports as well as laboratory results. Plant genome sequences made it possible to predict and characterize the genome-wide of putative endogenous allergens in rice (Oryza sativa L.). In this work, we identified and characterized 122 candidate rice allergens including the 22 allergens in present databases. Conserved domain analysis also revealed 37 domains among rice allergens including one novel domain (histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, PF13589) adding to the allergen protein database. Phylogenetic analysis of the allergens revealed the diversity among the Prolamin superfamily and DnaK protein family, respectively. Additionally, some allergens proteins clustered on the rice chromosome might suggest the molecular function during the evolution.

Topik & Kata Kunci

Toxicology. Poisons

Penulis (8)

Fang Chao Zhu

Rui Zong Jia

Lin Xu

Hua Kong

Yun Ling Guo

Qi Xing Huang

Yun Judy Zhu

An Ping Guo

Format Sitasi

APA MLA BibTeX

Zhu, F.C., Jia, R.Z., Xu, L., Kong, H., Guo, Y.L., Huang, Q.X. et al. (2015). Genome-wide analysis of potential cross-reactive endogenous allergens in rice (Oryza sativa L.). https://doi.org/10.1016/j.toxrep.2015.07.017

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Informasi Jurnal

Tahun Terbit: 2015
Sumber Database: DOAJ
DOI: 10.1016/j.toxrep.2015.07.017
Akses: Open Access ✓