DOAJ Open Access 2020

Neuroimaging in genetic frontotemporal dementia and amyotrophic lateral sclerosis

Suvi Häkkinen Stephanie A. Chu Suzee E. Lee

Abstrak

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) have a strong clinical, genetic and pathological overlap. This review focuses on the current understanding of structural, functional and molecular neuroimaging signatures of genetic FTD and ALS. We overview quantitative neuroimaging studies on the most common genes associated with FTD (MAPT, GRN), ALS (SOD1), and both (C9orf72), and summarize visual observations of images reported in the rarer genes (CHMP2B, TARDBP, FUS, OPTN, VCP, UBQLN2, SQSTM1, TREM2, CHCHD10, TBK1).

Topik & Kata Kunci

Neurosciences. Biological psychiatry. Neuropsychiatry

Penulis (3)

Suvi Häkkinen

Stephanie A. Chu

Suzee E. Lee

Format Sitasi

APA MLA BibTeX

Häkkinen, S., Chu, S.A., Lee, S.E. (2020). Neuroimaging in genetic frontotemporal dementia and amyotrophic lateral sclerosis. https://doi.org/10.1016/j.nbd.2020.105063

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.1016/j.nbd.2020.105063

Informasi Jurnal

Tahun Terbit: 2020
Sumber Database: DOAJ
DOI: 10.1016/j.nbd.2020.105063
Akses: Open Access ✓