DOAJ Open Access 2023

Amide proton transfer imaging of Alzheimer's disease and Parkinson's disease

Chunmei Li Jinyuan Zhou Di Wang Xinyang Li Shanshan Jiang +5 lainnya

Abstrak

Amide proton transfer (APT) magnetic resonance imaging (MRI) is an important molecular imaging technique at the protein level in tissue. Neurodegenerative diseases have a high likelihood of causing abnormal protein accumulation in the brain, which can be detected by APT MRI. This article briefly introduces the principles and image processing technology of APT MRI, and reviews the current state of research on Alzheimer's disease and Parkinson's disease using this technique. Early applications of this approach in these two neurodegenerative diseases are encouraging, which also suggests continued technical development and larger clinical trials to gauge the value of this technique.

Topik & Kata Kunci

Physical and theoretical chemistry Analytical chemistry

Penulis (10)

Chunmei Li

Jinyuan Zhou

Di Wang

Xinyang Li

Shanshan Jiang

Yi Zhang

Zhibo Wen

Guangbin Wang

Fuhua Yan

Min Chen

Format Sitasi

APA MLA BibTeX

Li, C., Zhou, J., Wang, D., Li, X., Jiang, S., Zhang, Y. et al. (2023). Amide proton transfer imaging of Alzheimer's disease and Parkinson's disease. https://doi.org/10.1016/j.mrl.2022.10.002

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Informasi Jurnal

Tahun Terbit: 2023
Sumber Database: DOAJ
DOI: 10.1016/j.mrl.2022.10.002
Akses: Open Access ✓