DOAJ Open Access 2024

Pioneering cord blood transplantation in relapsed/refractory HIV-related lymphoma: a case study with concurrent intramuscular antiretroviral therapy

Takako Yokota Shuhei Kurosawa Yukihiro Yoshimura Masato Bingo Tomoko Yamaguchi +9 lainnya

Abstrak

A 44-year-old HIV-positive man diagnosed with diffuse large B-cell lymphoma in 2021 achieved complete remission with six cycles of R-CHOP therapy but had a relapse in November 2022. ESHAP therapy failed to induce remission, leading to complete remission with four cycles of Pola-BR therapy. Post-failure of autologous stem cell harvest, cord blood transplantation (CBT) was performed in June 2023. Notably, this case used recently approved intramuscular antiretroviral therapy (ART) with cabotegravir and rilpivirine, addressing gastrointestinal complications during CBT. This innovative use of intramuscular ART in the treatment of malignancy represents a first in the field, offering a pioneering approach to HIV-related lymphoma.

Topik & Kata Kunci

Infectious and parasitic diseases

Penulis (14)

Takako Yokota

Shuhei Kurosawa

Yukihiro Yoshimura

Masato Bingo

Tomoko Yamaguchi

Yusuke Takada

Yuna So

Nobuyuki Miyata

Hitomi Nakayama

Aki Sakurai

Kosuke Sato

Chisako Ito

Yoshinobu Aisa

Tomonori Nakazato

Format Sitasi

APA MLA BibTeX

Yokota, T., Kurosawa, S., Yoshimura, Y., Bingo, M., Yamaguchi, T., Takada, Y. et al. (2024). Pioneering cord blood transplantation in relapsed/refractory HIV-related lymphoma: a case study with concurrent intramuscular antiretroviral therapy. https://doi.org/10.1016/j.ijid.2024.107124

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Informasi Jurnal

Tahun Terbit: 2024
Sumber Database: DOAJ
DOI: 10.1016/j.ijid.2024.107124
Akses: Open Access ✓