DOAJ Open Access 2023

Selective demyelination of a sciatic nerve allograft after SARS-CoV-2 infection – Case report

Magdalena Koszewicz Dorota Kaminska Jacek Martynkiewicz Adam Domanasiewicz Jerzy Gosk

Abstrak

Peripheral neurological complications are seen after SARS-CoV-2 infections. These are mostly immune-mediated such as Guillaine–Barré syndrome or chronic inflammatory demyelinating polyneuropathy. We present a 39-year-old man treated with a right sciatic nerve allotransplantation with subsequent clinical and electrophysiological improvement within 30 months of observation. After SARS-CoV-2 infection, he developed clinical deterioration with selective sciatic nerve demyelination in a nerve conduction study. Nerve conduction velocity returned to previous values within six months of treatment. Intravenous immunoglobulins were used at standard dosage. The inflammatory immune process seemed to be a cause of peripheral demyelination isolated to a nerve allograft with good reaction for intravenous immunoglobulin treatment.

Topik & Kata Kunci

Science (General) Social sciences (General)

Penulis (5)

Magdalena Koszewicz

Dorota Kaminska

Jacek Martynkiewicz

Adam Domanasiewicz

Jerzy Gosk

Format Sitasi

APA MLA BibTeX

Koszewicz, M., Kaminska, D., Martynkiewicz, J., Domanasiewicz, A., Gosk, J. (2023). Selective demyelination of a sciatic nerve allograft after SARS-CoV-2 infection – Case report. https://doi.org/10.1016/j.heliyon.2023.e20624

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Informasi Jurnal

Tahun Terbit: 2023
Sumber Database: DOAJ
DOI: 10.1016/j.heliyon.2023.e20624
Akses: Open Access ✓