DOAJ Open Access 2025

Rapid screening and taste mechanism of novel umami peptides from natural tripeptide database

Jing Lan Yongzhao Xiong Kuo Dang Daodong Pan Lihui Du +2 lainnya

Abstrak

Small peptides, particularly tripeptides, play a crucial role in food umami taste. To dig for more umami tripeptides, the novel tripeptides pharmacophore model was established to rapidly screen umami peptides from natural tripeptide database. Twenty peptides with potential umami characteristics from 8000 tripeptides were further screened by molecular docking. The electronic tongue analysis and sensory evaluation suggested that the 20 tripeptides exhibited umami taste characteristics. The thresholds of the 20 tripeptides spanned from 0.137 to 2.237 mmol/L. Molecular dynamics simulations were used on T1R1 and four tripeptides with high umami intensity to reveal their taste mechanisms. In this study, a new screening strategy was established and 20 new umami tripeptides were identified and validated, providing a theoretical reference for rapid screening of umami tripeptides.

Topik & Kata Kunci

Nutrition. Foods and food supply Food processing and manufacture

Penulis (7)

Jing Lan

Yongzhao Xiong

Kuo Dang

Daodong Pan

Lihui Du

Yanli Wang

Yali Dang

Format Sitasi

APA MLA BibTeX

Lan, J., Xiong, Y., Dang, K., Pan, D., Du, L., Wang, Y. et al. (2025). Rapid screening and taste mechanism of novel umami peptides from natural tripeptide database. https://doi.org/10.1016/j.fochx.2025.102565

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Informasi Jurnal

Tahun Terbit: 2025
Sumber Database: DOAJ
DOI: 10.1016/j.fochx.2025.102565
Akses: Open Access ✓