DOAJ Open Access 2023

Dietary antioxidants and lifespan: Relevance of environmental conditions, diet, and genotype of experimental models

Alfonso Varela-López José M. Romero-Márquez María D. Navarro-Hortal César L. Ramirez-Tortosa Maurizio Battino +2 lainnya

Lihat Sumber DOI

Abstrak

The rise of life expectancy in current societies is not accompanied, to date, by a similar increase in healthspan, which represents a great socio-economic problem. It has been suggested that aging can be manipulated and then, the onset of all age-associated chronic disorders can be delayed because these pathologies share age as primary underlying risk factor. One of the most extended ideas is that aging is consequence of the accumulation of molecular damage. According to the oxidative damage theory, antioxidants should slow down aging, extending lifespan and healthspan. The present review analyzes studies evaluating the effect of dietary antioxidants on lifespan of different aging models and discusses the evidence on favor of their antioxidant activity as anti-aging mechanisms. Moreover, possible causes for differences between the reported results are evaluated.

Topik & Kata Kunci

Medicine Biology (General)

Penulis (7)

Alfonso Varela-López

José M. Romero-Márquez

María D. Navarro-Hortal

César L. Ramirez-Tortosa

Maurizio Battino

Tamara Y. Forbes-Hernández

José L. Quiles

Format Sitasi

APA MLA BibTeX

Varela-López, A., Romero-Márquez, J.M., Navarro-Hortal, M.D., Ramirez-Tortosa, C.L., Battino, M., Forbes-Hernández, T.Y. et al. (2023). Dietary antioxidants and lifespan: Relevance of environmental conditions, diet, and genotype of experimental models. https://doi.org/10.1016/j.exger.2023.112221

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.1016/j.exger.2023.112221

Informasi Jurnal

Tahun Terbit: 2023
Sumber Database: DOAJ
DOI: 10.1016/j.exger.2023.112221
Akses: Open Access ✓