DOAJ Open Access 2015

Biotransformation of furanocoumarins by Cunninghamella elegans

Ghada Ismail El-shahat Ali Attia Kamillia A. Abou-El-seoud Abdel-Rahim Sayed Ibrahim

Abstrak

Biotransformation of Furanocoumarins; psoralen (1), bergapten (2), xanthotoxin (3) and imperatorin (4) was explored by Cunninghamella elegans NRRL 1392, revealing the metabolism of psoralen (1) and bergapten (2) into bergaptol (5), while xanthotoxin (3) and imperatorin (4) were converted into xanthotoxol (6). On the other hand unexpected conversion of xanthotoxin (3) into 3,4 dihydroxanthotoxin (7) occurred. The structure of the isolated pure metabolites was established using physical and spectroscopic techniques including, melting points, IR, 1H NMR, 13C NMR and mass spectroscopy.

Topik & Kata Kunci

Therapeutics. Pharmacology Pharmacy and materia medica Pharmaceutical industry

Penulis (3)

Ghada Ismail El-shahat Ali Attia

Kamillia A. Abou-El-seoud

Abdel-Rahim Sayed Ibrahim

Format Sitasi

APA MLA BibTeX

Attia, G.I.E.A., Abou-El-seoud, K.A., Ibrahim, A.S. (2015). Biotransformation of furanocoumarins by Cunninghamella elegans. https://doi.org/10.1016/j.bfopcu.2014.09.001

Akses Cepat

PDF tidak tersedia langsung

Cek di sumber asli →

Lihat di Sumber doi.org/10.1016/j.bfopcu.2014.09.001

Informasi Jurnal

Tahun Terbit: 2015
Sumber Database: DOAJ
DOI: 10.1016/j.bfopcu.2014.09.001
Akses: Open Access ✓