Electrochemical Reduction of Carbamazepine in Ethanol and Water Solutions Using a Glassy Carbon Electrode.
Abstrak
The electrochemical reduction of carbamazepine in ethanol and water using a glassy carbon electrode has been studied. In all experimental conditions of scan rate and concentration of carbamazepine an irreversible cathodic wave was observed by cyclic voltammetry (CV). Electrochemical parameters and a plausible EqC mechanism have been reported from the electrochemical measurements and digital simulation. The values of thermodynamic E1/2 were correlated with solvent polarity parameters that it can be interesting for biological, pharmaceutical and forensic purposes. Limits of Detection (LOD) for DPV are 1.1 and 9.0 μg/mL (4.65x10-6 and 3.81x10-5 M) in ethanol and water, respectively. The precision and recoveries obtained for tablets and plasma samples showed that the method could be successfully used for analysis.
Topik & Kata Kunci
Penulis (6)
S. Atkins
R.Jimenez- Perez
J.M. Sevilla
M. Blazquez
T. Pineda
J.Gonzalez- Rodriguez
Akses Cepat
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- 2013
- Sumber Database
- DOAJ
- DOI
- 10.1016/S1452-3981(23)14290-8
- Akses
- Open Access ✓