DOAJ Open Access 2025

A Case of Concomitant Lung Adenocarcinoma and Pleural Metastasis of Papillary Thyroid Carcinoma With BRAF V600E Mutation

Akinari Atsumi Tetsuo Tani Kota Ishioka Keisuke Nishikawa Yasuhide Okamoto +1 lainnya

Abstrak

ABSTRACT A 62‐year‐old woman with a history of papillary thyroid carcinoma presented to our hospital with fever and cough and was diagnosed with stage IV non‐small cell lung carcinoma (NSCLC). One year after chemoimmunotherapy, a re‐biopsy of the left pleural tumour lesion was performed. Histological analysis revealed papillary thyroid carcinoma. Another biopsy was performed on the primary tumour, and the histological analysis of the primary tumour lesion confirmed NSCLC. BRAF V600E mutations were detected in both left pleural metastatic lesions of papillary thyroid carcinoma and the primary tumour of NSCLC. Dabrafenib and trametinib reduced both tumour lesions. Here, we report a rare case of concomitant BRAF V600E‐mutated NSCLC and pleural metastasis from papillary thyroid carcinoma.

Topik & Kata Kunci

Diseases of the respiratory system

Penulis (6)

Akinari Atsumi

Tetsuo Tani

Kota Ishioka

Keisuke Nishikawa

Yasuhide Okamoto

Saeko Takahashi

Format Sitasi

APA MLA BibTeX

Atsumi, A., Tani, T., Ishioka, K., Nishikawa, K., Okamoto, Y., Takahashi, S. (2025). A Case of Concomitant Lung Adenocarcinoma and Pleural Metastasis of Papillary Thyroid Carcinoma With BRAF V600E Mutation. https://doi.org/10.1002/rcr2.70119

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Informasi Jurnal

Tahun Terbit: 2025
Sumber Database: DOAJ
DOI: 10.1002/rcr2.70119
Akses: Open Access ✓