Research progress on structure and catalytic mechanism of dextranase
Abstrak
Abstract Dextranase is an important industrial enzyme for the preparation of isomalto‐oligosaccharides. According to the crystal structures of 20 dextranases of four classes, we summarized the structural characteristics of enzymes and the binding modes of enzymes and ligands in this paper. Based on the characteristics of the products, we analyzed the characteristics of the binding domain and functions of dextranase by means of molecular simulation and molecular docking. The relationship between the product specificity of dextranase, its catalytic pocket shape, and its catalytic mode was briefly summarized. The catalytic mechanism of dextranase was systematically discussed, which provided the basis and reference for the rational transformation of dextranase.
Topik & Kata Kunci
Penulis (6)
Xue‐Qin Hu
Bing‐Bing Xia
Wei‐Juan Ru
Yu‐Xin Zhang
Jing‐Wen Yang
Hong‐Bin Zhang
Akses Cepat
- Tahun Terbit
- 2023
- Sumber Database
- DOAJ
- DOI
- 10.1002/efd2.60
- Akses
- Open Access ✓