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CrossRef Open Access 2025 2 sitasi

Physical Function as Assessed by the Liver Frailty Index Remains Stable Over Time in Patients With Hepatocellular Carcinoma Treated With Locoregional Therapies

Madeleine D. Hu Sy Han Chiou Molly Delk Cynthia Fenton Jennifer C. Lai +1 lainnya
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Abstrak

INTRODUCTION: It is unknown how frailty evolves over time in patients with hepatocellular carcinoma who are treated with locoregional therapies (LRTs). METHODS: We conducted a retrospective study of LRT-treated hepatocellular carcinoma patients with Liver Frailty Index (LFI) assessments. Linear mixed-effects modeling was used to assess the impact of time (modeled linearly per month) and other variables on LFI. RESULTS: Of 201 patients enrolled, median baseline LFI was 3.54. LFI did not change significantly over time from study entry (P = 0.93). DISCUSSION: In our study, LFI remained stable over time after LRT, suggesting that LRT is generally well tolerated.

Penulis (6)

M

Madeleine D. Hu

S

Sy Han Chiou

M

Molly Delk

C

Cynthia Fenton

J

Jennifer C. Lai

M

Michael Li

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Hu, M.D., Chiou, S.H., Delk, M., Fenton, C., Lai, J.C., Li, M. (2025). Physical Function as Assessed by the Liver Frailty Index Remains Stable Over Time in Patients With Hepatocellular Carcinoma Treated With Locoregional Therapies. https://doi.org/10.14309/ctg.0000000000000854

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Informasi Jurnal
Tahun Terbit
2025
Bahasa
en
Total Sitasi
2×
Sumber Database
CrossRef
DOI
10.14309/ctg.0000000000000854
Akses
Open Access ✓