CrossRef Open Access 2024 4 sitasi

On a mathematical model for cancer invasion with repellent pH-taxis and nonlocal intraspecific interaction

Maria Eckardt Christina Surulescu

Abstrak

AbstractStarting from a mesoscopic description of cell migration and intraspecific interactions, we obtain by upscaling an effective reaction–diffusion–taxis equation for the cell population density involving spatial nonlocalities in the source term and biasing its motility and growth behavior according to environmental acidity. We prove global existence, uniqueness, and boundedness of a nonnegative solution to a simplified version of the coupled system describing cell and acidity dynamics. A 1D study of pattern formation is performed. Numerical simulations illustrate the qualitative behavior of solutions.

Penulis (2)

M

Maria Eckardt

C

Christina Surulescu

Format Sitasi

Eckardt, M., Surulescu, C. (2024). On a mathematical model for cancer invasion with repellent pH-taxis and nonlocal intraspecific interaction. https://doi.org/10.1007/s00033-024-02189-9

Akses Cepat

Lihat di Sumber doi.org/10.1007/s00033-024-02189-9
Informasi Jurnal
Tahun Terbit
2024
Bahasa
en
Total Sitasi
Sumber Database
CrossRef
DOI
10.1007/s00033-024-02189-9
Akses
Open Access ✓