arXiv Open Access 2005

Role-similarity based functional prediction in networked systems: Application to the yeast proteome

Petter Holme Mikael Huss

Lihat Sumber

Abstrak

We propose a general method to predict functions of vertices where: 1. The wiring of the network is somehow related to the vertex functionality. 2. A fraction of the vertices are functionally classified. The method is influenced by role-similarity measures of social network analysis. The two versions of our prediction scheme is tested on model networks were the functions of the vertices are designed to match their network surroundings. We also apply these methods to the proteome of the yeast Saccharomyces cerevisiae and find the results compatible with more specialized methods.

Topik & Kata Kunci

q-bio.MN cond-mat.other q-bio.OT

Penulis (2)

Petter Holme

Mikael Huss

Format Sitasi

APA MLA BibTeX

Holme, P., Huss, M. (2005). Role-similarity based functional prediction in networked systems: Application to the yeast proteome. https://arxiv.org/abs/q-bio/0503010

Akses Cepat

Lihat di Sumber

Informasi Jurnal

Tahun Terbit: 2005
Bahasa: en
Sumber Database: arXiv
Akses: Open Access ✓