arXiv Open Access 2024

Modeling the hallmarks of avascular tumors

Erik Blom Stefan Engblom Gesina Menz

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Abstrak

We present a stochastic computational model of avascular tumors, emphasizing the detailed implementation of the first four so-called hallmarks of cancer: self-sufficiency in growth factors, resistance to growth inhibitors, avoidance of apoptosis, and unlimited growth potential. Our goal is to provide a foundational understanding of the first steps of cancer malignancy while addressing modeling uncertainties, thus bringing us closer to a first-principles grasp of this process. Preliminary numerical simulations illustrate the comprehensiveness of our perspective.

Topik & Kata Kunci

q-bio.PE math.DS

Penulis (3)

Erik Blom

Stefan Engblom

Gesina Menz

Format Sitasi

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Blom, E., Engblom, S., Menz, G. (2024). Modeling the hallmarks of avascular tumors. https://arxiv.org/abs/2402.01305

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Informasi Jurnal

Tahun Terbit: 2024
Bahasa: en
Sumber Database: arXiv
Akses: Open Access ✓