arXiv
Open Access
2021
How to address cellular heterogeneity by distribution biology
Niko Komin
Alexander Skupin
Abstrak
Cellular heterogeneity is an immanent property of biological systems that covers very different aspects of life ranging from genetic diversity to cell-to-cell variability driven by stochastic molecular interactions, and noise induced cell differentiation. Here, we review recent developments in characterizing cellular heterogeneity by distributions and argue that understanding multicellular life requires the analysis of heterogeneity dynamics at single cell resolution by integrative approaches that combine methods from non-equilibrium statistical physics, information theory and omics biology.
Topik & Kata Kunci
Penulis (2)
N
Niko Komin
A
Alexander Skupin
Akses Cepat
Informasi Jurnal
- Tahun Terbit
- 2021
- Bahasa
- en
- Sumber Database
- arXiv
- Akses
- Open Access ✓