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arXiv Open Access 2014

Rosetta Brains: A Strategy for Molecularly-Annotated Connectomics

Adam H Marblestone Evan R Daugharthy Reza Kalhor Ian D Peikon Justus M Kebschull +7 lainnya
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Abstrak

We propose a neural connectomics strategy called Fluorescent In-Situ Sequencing of Barcoded Individual Neuronal Connections (FISSEQ-BOINC), leveraging fluorescent in situ nucleic acid sequencing in fixed tissue (FISSEQ). FISSEQ-BOINC exhibits different properties from BOINC, which relies on bulk nucleic acid sequencing. FISSEQ-BOINC could become a scalable approach for mapping whole-mammalian-brain connectomes with rich molecular annotations.

Topik & Kata Kunci

q-bio.NC

Penulis (12)

A

Adam H Marblestone

E

Evan R Daugharthy

R

Reza Kalhor

I

Ian D Peikon

J

Justus M Kebschull

S

Seth L Shipman

Y

Yuriy Mishchenko

J

Je Hyuk Lee

K

Konrad P Kording

E

Edward S Boyden

A

Anthony M Zador

G

George M Church

Format Sitasi

APA MLA BibTeX
Marblestone, A.H., Daugharthy, E.R., Kalhor, R., Peikon, I.D., Kebschull, J.M., Shipman, S.L. et al. (2014). Rosetta Brains: A Strategy for Molecularly-Annotated Connectomics. https://arxiv.org/abs/1404.5103

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Tahun Terbit
2014
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en
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arXiv
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Open Access ✓