arXiv Open Access 2012

Signalling noise enhances chemotactic drift of E. coli

Marlo Flores Thomas S. Shimuzu Pieter Rein ten Wolde Filipe Tostevin
Lihat Sumber

Abstrak

Noise in transduction of chemotactic stimuli to the flagellar motor of E. coli will affect the random run-and-tumble motion of the cell and the ability to perform chemotaxis. Here we use numerical simulations to show that an intermediate level of noise in the slow methylation dynamics enhances drift while not compromising localisation near concentration peaks. A minimal model shows how such an optimal noise level arises from the interplay of noise and the dependence of the motor response on the network output. Our results suggest that cells can exploit noise to improve chemotactic performance.

Topik & Kata Kunci

Penulis (4)

M

Marlo Flores

T

Thomas S. Shimuzu

P

Pieter Rein ten Wolde

F

Filipe Tostevin

Format Sitasi

Flores, M., Shimuzu, T.S., Wolde, P.R.t., Tostevin, F. (2012). Signalling noise enhances chemotactic drift of E. coli. https://arxiv.org/abs/1208.5360

Akses Cepat

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Tahun Terbit
2012
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en
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arXiv
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Open Access ✓